Ali’s hand started SHAKING in round 8 — neurologists revealed the trut JJ
October 2, 1980. Muhammad Ali was fighting Larry Holmes for the heavyweight championship when something terrifying happened in round eight. His left hand started shaking uncontrollably between punches. The ringside doctor saw it. Ali’s corner saw it, but nobody stopped the fight. What happened in those three rounds would change Ali’s life forever. And neurologists who analyzed the footage 25 years later would confirm what nobody wanted to believe. This was the night Parkinson’s disease began.
Las Vegas, Nevada, Caesar’s Palace. Muhammad Ali, 38 years old, coming out of retirement for one more shot at glory. His opponent, Larry Holmes, the reigning heavyweight champion, undefeated in 35 fights, 27 years old, and in his absolute prime. This fight never should have happened. Ali had retired in 1979 after losing to Leon Spinx in their rematch. He’d accomplished everything, regained his title three times, fought in the most famous bouts in boxing history, become the most recognized athlete on earth. He
had nothing left to prove. But Ali was also broke. Years of bad investments, expensive divorce settlements, supporting dozens of family members and friends, and the IRS demanding back taxes had left him desperate for money. When promoters offered him $8 million to fight Holmes, his former sparring partner who’d become champion, Ali couldn’t refuse. Everyone close to Ali begged him not to take the fight. His doctor, Ferdie Pacheco, had resigned from Ali’s corner two years earlier, warning that continued fighting would
cause permanent brain damage. Angelo Dundee, Ali’s longtime trainer, tried to talk him out of it. Even Larry Holmes himself had privately told Ali, “Please don’t do this. I don’t want to hurt you.” But Ali needed the money. And somewhere deep inside, he still believed he was the greatest, that he could turn back time one more time, that he could somehow beat the younger, stronger, faster Holmes. He couldn’t, and everyone knew it before the first bell rang. The fight was brutal from the start. Holmes,
conflicted about beating his idol, but professional enough to do his job, dominated every round. Ali looked slow, tired, unable to mount any offense. His famous footwork was gone. His lightning fast jab was now plotting and predictable. Holmes landed punch after punch while Ali covered up, absorbed the blows, and tried desperately to survive. By round seven, Ali had barely won a single exchange. His face was swelling. His corner was panicking. Angelo Dundee was begging him to show something, anything that resembled the fighter Ali

injuries to know this wasn’t fatigue. This was neurological. He made a note on his card to watch Ali closely. Round eight began. Holmes continued his assault. Ali tried to fight back, but his punches had no power, no speed, and between exchanges, when Ali would lower his hands for just a moment. The tremor in his left hand became visible to those watching closely. The television commentators didn’t notice it. The crowd of 24,790 didn’t see it. But in Ali’s corner, Angelo Dundee saw it. And in the
opposite corner, Larry Holmes’s trainer, Richie Giaetti, saw it. And at ringside, Dr. Romeo, saw it clearly. “Something’s wrong with Ali,” Giaetti said to Holmes between rounds. “His hand is shaking. His movement is off. Be careful. He might collapse.” Holmes had noticed it, too. He’d been Ali’s sparring partner for years in the 1970s. He knew every move Ali made, every mannerism, every habit. This shaking hand wasn’t normal. This was something new, something wrong.
Round nine was worse. Ali could barely hold his hands up. When he did throw punches, his left hand trembled noticeably in the follow-through. Holmes, showing mercy despite his professional obligation, started pulling his punches slightly, not wanting to cause permanent damage to the man he’d once idolized. Dr. Romeo approached the ring apron. I’m watching him closely, he told the referee, Richard Green. If he gets worse, we stop it. In Ali’s corner, Dundee was nearly in tears. Champ, I
need to stop this, he said, looking into Ali’s swollen eyes. You’re hurt. Something’s wrong. No, Ali said, his words slightly slurred. Not yet. Let me finish. Ali, your hand. One more round, Ali interrupted. Give me one more. Round 10 began. By now, anyone watching closely could see that something was terribly wrong with Muhammad Ali. His movements were stiff. His hands shook between punches. His balance was off. Holmes landed combinations at Will and Ali barely reacted. 45 seconds into
round 10, Holmes hit Ali with a right hand that snapped his head back. Ali’s legs buckled. He grabbed the ropes to stay upright. His left hand was shaking violently now, clearly visible even on television. That’s when Dr. Romeo climbed the ring steps. “Stop it,” he told the referee. “Stop the fight now.” Richard Green looked at Ali, saw the trembling hand, saw the glazed eyes, and immediately waved his arms. That’s it. Fight’s over. The fight was stopped at 255 of round 10. Technical knockout.
Larry Holmes remained undefeated heavyweight champion. Muhammad Ali’s career was effectively over. In the dressing room after the fight, Ali collapsed, not from the punches, but from complete exhaustion. His left hand was still trembling. Medical staff rushed to examine him. Dr. Romeo’s post-fight report, which wouldn’t be made public for years, included this notation. Fighter exhibited unusual tremors in left hand, persisting for multiple rounds. Tremor appeared involuntary and unrelated to fatigue.
Recommended immediate neurological examination. That examination never happened, at least not immediately. Ali refused, saying he was just tired, just old, just done with boxing. He went back to his hotel, counted his $8 million payday, and tried to forget the worst beating of his career. But the tremor didn’t go away. Over the next few weeks, it persisted. Then it started appearing in his right hand, too. His speech began to slur occasionally. His movements became slightly stiffer. By early 1981,
Ali’s wife, Veronica, was seriously worried. She’d noticed him having trouble with simple tasks, buttoning his shirt, signing autographs, even walking seemed difficult. She finally convinced him to see a neurologist. The diagnosis came in 1984, though Ali’s family suspected it earlier. Parkinson’s disease, a progressive neurological disorder that affects movement, causes tremors, and has no cure. For years, the public narrative was that Ali’s Parkinson’s was caused by decades of
accumulated head trauma from boxing. All those punches, all those fights, all that damage adding up over time. And that’s certainly part of the truth. But in 2005, a group of neurologists at UCLA decided to do something unprecedented. They obtained footage of Ali’s fights from the 1970s and early 1980s and analyzed them frame by frame, looking for early signs of Parkinson’s symptoms. What they discovered was shocking. The UCLA team led by Dr. Abraham Lieberman, a leading Parkinson’s specialist,
published their findings in a neurology journal. Their conclusion, Muhammad Ali showed clear visible signs of Parkinson’s disease during the Holmes fight in October 1980, specifically in rounds 8, 9, and 10. The tremor in Ali’s left hand is classic resting tremor, a hallmark of Parkinson’s, Dr. Lieberman wrote. the stiffness in his movements, the balance issues, the slowed reactions. These weren’t just fatigue or age or accumulated damage. These were early Parkinson symptoms manifesting in
real time during the fight. The study went further. They analyzed earlier fights and found subtle signs going back to the late 1970s, minor movement issues in the third Frasier fight in 1975, slight hand trimmers in the Ernie Shavers fight in 1977. But the Holmes fight was when the symptoms became undeniable. The trauma of that fight, the repeated head blows, the physical stress, the extreme exertion likely accelerated the disease process, Dr. Lieberman explained in interviews. Parkinson’s doesn’t start
suddenly. It develops over years, but major trauma can cause symptoms to appear more rapidly. The Holmes fight was that trigger event. The most heartbreaking part of the study’s findings was this. The ringside doctor was right. Dr. Romeo had seen the symptoms in real time, had documented them, had even considered stopping the fight earlier, but nobody understood what they were seeing. Nobody recognized it as Parkinson’s because Ali was only 38, and Parkinson’s typically affects people over 60. If they’d known, would
they have stopped the fight sooner? Would they have prevented Ali from taking those additional two rounds of punishment? Would it have made any difference in the long-term progression of his disease? We’ll never know. What we do know is that the Holmes fight was the beginning of the end for Muhammad Ali as the man the world knew. He fought one more time against Trevor Berbick in December 1981, losing a decision in a fight that was painful to watch. Then he retired for good. Over the next 35
years, Parkinson slowly ravaged Ali’s body. The tremors got worse. His speech became increasingly difficult to understand. His famous quick wit was trapped inside a body that wouldn’t cooperate. By the 1990s, he could barely speak above a whisper. But here’s what makes this story remarkable. Ali never complained. never expressed regret about the Holmes fight, about continuing to box too long, about the price he paid for his career. In 1996, when Ali lit the Olympic flame at the Atlanta Games,
the whole world watched as his hand trembled holding the torch. It was heartbreaking and inspirational at the same time. Ali, disabled by Parkinson’s, still standing proud, still representing excellence and courage. In interviews late in his life, when he could still communicate effectively, Ali was asked about the Holmes fight, asked if he regretted it, asked if he knew something was wrong even then. His answer delivered slowly but clearly. I felt different that night. Something was changing. But I was Ali. I was the
greatest. I thought I could beat anything, even my own body. I was wrong. Larry Holmes, who went on to defend his title 20 times and became one of the greatest heavyweights in history, never celebrated beating Ali. He said in multiple interviews that the Holmes Ali fight was the saddest night of his boxing career. I didn’t want to hurt him,” Holmes said years later. I could see something was wrong. His hand was shaking. He wasn’t moving right. But what could I do? Stop fighting? He was
still Muhammad Ali. He was still in the ring. I had to do my job. But I hated every second of it. When Holmes learned about the UCLA study in 2005 that the Parkinson symptoms had been visible during their fight, he was devastated. You mean I was watching him develop Parkinson’s in real time and none of us knew it? I was hitting a man who was already sick. That kills me. That really kills me. Holmes reached out to Ali after the study was published. They met privately, and Holmes apologized for the
beating he’d given Ali that night. Ali, his voice barely audible, told Holmes he had nothing to apologize for. You were the better man that night. You did your job. I should have stopped earlier, not your fault. Dr. Fertie Pacheo, Ali’s former doctor, who’d resigned before the Holmes fight specifically to avoid watching Ali suffer permanent damage, gave numerous interviews about the 2005 UCLA study. I’d been warning about neurological damage for years. Pacheo said, “I knew continued fighting would destroy Ali. I
just didn’t know it would be Parkinson’s specifically.” When I saw that study, when I saw the footage of his hand shaking in round eight, I felt sick because I knew that if I’d still been in his corner, if I’d been at that fight, I would have stopped it right then. I would have recognized neurological symptoms and ended it. But I wasn’t there. Nobody was there who understood what they were seeing. Angelo Dundy, who was in Ali’s corner that night, watched the UCLA study footage before he died in
2012. He gave one final interview about it. I saw his hands shaking. I saw something was wrong, but I didn’t know what it was. I thought maybe nerve damage, maybe fatigue, maybe something temporary. If I’d known it was the beginning of Parkinson’s, if id known that every punch he took after that was making it worse, I would have stopped the fight myself. I would have thrown in the towel. But I didn’t know. None of us knew. And Ali paid the price for our ignorance. The homes fight has become a
case study in sports medicine programs. It’s used to teach doctors how to recognize early neurological symptoms, how trauma can accelerate disease processes, and why it’s crucial to stop athletic competitions when something seems wrong, even if you don’t know exactly what’s wrong. Muhammad Ali died on June 3rd, 2016 after three decades of living with Parkinson’s disease. The disease took his voice, his movement, his independence, but it never took his spirit. Until the very end, he remained
the greatest. Not because he never lost, but because he never gave up. The night of October 2nd, 1980 wasn’t just about a boxing match. It was about the moment when a disease began to manifest, when a body started to betray the mind inside it, when the price of a lifetime of combat started coming due. Muhammad Ali showed symptoms of Parkinson’s disease in rounds 8, 9, and 10 of his fight against Larry Holmes. Everyone saw it. Nobody recognized it. And by the time anyone understood what had happened, it
was too late to change anything. But Ali’s legacy isn’t diminished by this tragedy. If anything, it’s enhanced because knowing that he was fighting the early stages of a neurological disease during those rounds, knowing that every punch was becoming harder to throw, every movement more difficult, every moment in that ring a battle not just against Holmes, but against his own failing body, that makes his courage even more remarkable. He didn’t know he had Parkinson’s that night, but some
part of him knew something was wrong, and he kept fighting anyway. Because that’s what Muhammad Ali did. He fought. Always fought. Even when his opponent was inside his own body, even when the battle was already lost, even when the only thing left was the fighting itself. That night in Las Vegas, in rounds 8 through 10, the world watched Muhammad Ali begin to lose a fight he would spend the next 36 years fighting. A fight against Parkinson’s disease. A fight he couldn’t win, but a fight he never
stopped fighting until the very end. If this story moves you, remember true courage isn’t about never being afraid or never being hurt. It’s about continuing forward even when your body is failing, even when the odds are impossible. Even when the fight is already lost. Muhammad Ali showed us that courage in the ring against Holmes. And he showed us that same courage every day for 36 years afterward. That’s what made him the
